Genome-wide CRISPR screen for Zika virus resistance in human neural cells [Medical Sciences]
Zika virus (ZIKV) is a neurotropic and neurovirulent arbovirus that has severe detrimental impact on the developing human fetal brain. To date, little is known about the factors required for ZIKV infection of human neural cells. We identified ZIKV host genes in human pluripotent stem cell (hPSC)-derived neural progenitors (NPs)...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Yun Li, Julien Muffat, Attya Omer Javed, Heather R. Keys, Tenzin Lungjangwa, Irene Bosch, Mehreen Khan, Maria C. Virgilio, Lee Gehrke, David M. Sabatini, Rudolf Jaenisch Tags: Biological Sciences Source Type: research
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