Role of syndecan-1 and exogenous heparin in hepatoma sphere formation.

In conclusion, we found that SDC1 affected CSC marker CD13 and CD44 expression. SDC1 proteoglycan and heparin components changed and affected hepatoma sphere development. Application of heparin mimics in reduction of hepatoma stem cells might be potential. PMID: 31042409 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31042409?dopt=Abstract

Source: Biochemistry and Cell Biology - April 30, 2019 Category: Biochemistry Authors: Lin SC, Wu CP, Tseng T, Jhang Y, Lee S Tags: Biochem Cell Biol Source Type: research