Should You Get a Measles Booster Shot? Here ’s What Experts Say

Unvaccinated individuals have been the focus of attention during this year’s measles outbreaks. A record 704 cases of the illness have been confirmed in 22 states so far in 2019, and the CDC says the majority of those diagnoses have been in unvaccinated people. Health officials have repeatedly warned nearly everyone to get the shot if they haven’t already — sometimes threatening fines for those who refuse. “Over 90% of the measles cases that have occurred in the U.S. have occurred in unvaccinated persons,” says Dr. William Schaffner, a professor of preventive medicine and infectious diseases at the Vanderbilt University School of Medicine. “The emphasis needs to be on getting as many unvaccinated people vaccinated as possible.” But are those who have already been vaccinated safe, or might they need extra protection? Here’s what to know about measles booster shots. How effective is the measles vaccine? Currently, the Centers for Disease Control and Prevention (CDC) recommends that children get two doses of the measles, mumps and rubella (MMR) vaccine, unless they have specific allergies or prohibitive medical conditions. The first dose should be administered between 12 and 15 months, the CDC says, while the second should be given to kids ages four through six. But until 1989, the CDC only recommended that children get one dose of the vaccine. Two doses of the shot are about 97% effective at preventing the measles, while one dose...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized public health Source Type: news

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This study aimed to evaluate: (i) the effectiveness of plasma activated water (PAW) on the germination capacity of mung bean seeds and (ii) the antimicrobial capacity of PAW. A specially designed set-up composed of two electrochemical cell was used to produce two different types of PAW, by surface plasma discharge ignited from copper cathode and copper anode, respectively. The germination capacity of mung bean seeds was assessed over 96 h incubation in the dark at 25 °C. The antimicrobial capacity of PAW was assessed against 6 h exposure to Escherichia coli NCTC 12900. The anodic PAW (rich in NO3−) indicate...
Source: Food Control - Category: Food Science Source Type: research
Publication date: Available online 19 February 2020Source: Research in Veterinary ScienceAuthor(s): Ying-Feng Sun, Xuan Jiang, Ao Zhang, Ji-Fei Ma, Xiao-Xue Yu, Liu-An Li, Hai YuAbstractModified-live virus (MLV) vaccines derived from highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) were wildly used in China, which resulted in the emergence of MLV-like strains in pigs. Previous studies demonstrated that secondary bacterial infection could enhance HP-PRRSV infection-mediated inflammatory responses, but it is unknown whether early bacterial infection could enhance the HP-PRRSV MLV-like infectio...
Source: Research in Veterinary Science - Category: Veterinary Research Source Type: research
Conclusions: Docetaxel and epirubicin neoadjuvant chemotherapy showed a good response in locally advanced breast cancer. Pretreatment Ki-67 and change of Ki-67 may play a role as predictive factor for response to neoadjuvant chemotherapy. PMID: 32069523 [PubMed - as supplied by publisher]
Source: The Korean Journal of Internal Medicine - Category: Internal Medicine Authors: Tags: Korean J Intern Med Source Type: research
In conclusion, as the dose rates at a 1-m distance from patients upon release were
Source: Radiation Physics and Chemistry - Category: Physics Source Type: research
In this study, we proposed a Graph Convolutional Network (GCN) model to predict synergistic drug combinations in particular cancer cell lines. Specifically, the GCN method used a convolutional neural network model to do heterogeneous graph embedding, and thus solved a link prediction task. The graph in this study was a multimodal graph, which was constructed by integrating the drug-drug combination, drug-protein interaction, and protein–protein interaction networks. We found that the GCN model was able to correctly predict cell line-specific synergistic drug combinations from a large heterogonous network. The ma...
Source: Computational and Structural Biotechnology Journal - Category: Biotechnology Source Type: research
Publication date: Available online 19 February 2020Source: Biosensors and BioelectronicsAuthor(s): Amin Hassanzadeh-Barforoushi, Majid Ebrahimi Warkiani, David Gallego-Ortega, Guozhen Liu, Tracie BarberAbstractCancer cells continuously secrete inflammatory biomolecules which play significant roles in disease progression and tumor metastasis toward secondary sites. Despite recent efforts to capture cancer cells' intercellular secretion heterogeneity using microfluidics, the challenges in operation of these systems as well as the complexity of designing a biosensing assay for long-term and real-time measurement of single cel...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Authors: Iwamoto M, Gotoda T, Noda Y, Esaki M, Moriyama M, Yoshida N, Takayama T, Kobayashi H, Masuda S Abstract As gastric neuroendocrine carcinoma (NEC) is a rapidly growing cancer, most cases are diagnosed at advanced stages. We herein report a 74-year-old woman with an early-stage gastric NEC whose history included endoscopic submucosal dissection treatment for three early-stage gastric cancer lesions five years prior to the current presentation. We also describe the changes observed over time. An endoscopic examination during follow-up revealed an NEC (measuring 6 mm) in the gastric vestibule, for which distal...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Conclusion Based on the RR, Conv R, and symptom palliation ability, mFOLFOXIRI+α was suggested to be a viable candidate for first-line treatment for patients with ARCC, especially those with a high tumor burden. PMID: 32074573 [PubMed - as supplied by publisher]
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
In conclusion, (+)-FUC-TMC-NP is promising anthrax vaccine adjuvant as an alternative to CpG.
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Publication date: March 2020Source: Advances in Medical Sciences, Volume 65, Issue 1Author(s): Javad Masoumi, Abdollah Jafarzadeh, Hossein Khorramdelazad, Morteza Abbasloui, Jalal Abdolalizadeh, Najmeh JamaliAbstractApelin is an endogenous peptide, which is expressed in a vast board of organs such as the brain, placenta, heart, lungs, kidneys, pancreas, testis, prostate and adipose tissues. The apelin receptor, called angiotensin-like-receptor 1 (APJ), is also expressed in the brain, spleen, placenta, heart, liver, intestine, prostate, thymus, testis, ovary, lungs, kidneys, stomach, and adipose tissue. The apelin/APJ axis ...
Source: Advances in Medical Sciences - Category: Biomedical Science Source Type: research
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