Memory could be better protected in kids with brain tumors if treated with proton therapy

(European Society for Radiotherapy and Oncology (ESTRO)) A comparison of three types of radiotherapy for children's brain tumors suggests that a type of proton therapy called pencil beam scanning offers the best hope of preserving cognitive functions.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news

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Abstract Recent reports describe how genome-wide transcriptional analysis of cancer tissues can be exploited to identify molecular signatures of immune infiltration in cancer. We hypothesize that immune infiltration in cancer may also be defined by changes in certain epigenetic signatures. In this context, a primary objective is to identify site-specific CpG markers whose levels of methylation may be highly indicative of known transcriptional markers of immune infiltration such as GZMA, PRF1, T cell receptor genes, PDCD1, and CTLA4. This has been accomplished by integrating genome-wide transcriptional expression a...
Source: Advances in Cancer Research - Category: Cancer & Oncology Authors: Tags: Adv Cancer Res Source Type: research
CANCER: Brain tumours affect people of any age, including children, although they tend to be more common in older adults. Survival rates will depend on a range of factors, such as age and the part of the brain affected. Have you noticed this early warning sign?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Glioblastoma (GBM) is an aggressive brain tumor with universal recurrence and poor prognosis. The recurrence is largely driven by chemoradiation resistant cancer stem cells (CSCs). Epidermal growth factor rece...
Source: Journal of Experimental and Clinical Cancer Research - Category: Cancer & Oncology Authors: Tags: Research Source Type: research
BOSTON (CBS) — Researchers in Finland have developed a so-called “artificial nose” that they believe can help sniff out brain cancer during surgery. Surgeons often use an electric knife, particularly when operating on the brain. As the knife cuts, it burns through tissue, releases molecules into the air in the form of surgical smoke. Researchers developed a way to feed this smoke into a measuring system that has been taught to recognize smoke molecules from malignant tissue versus that from healthy tissue. In a study of almost 700 tissue samples, the device was at least 83 percent accurate at finding the ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Healthwatch Seen On WBZ-TV Syndicated Local brain tumors Dr. Mallika Marshall Source Type: news
Accurate segmentation of brain tumors is vital for the gross tumor volume (GTV) definition in radiotherapy. Functional MR images like apparent diffusion constant (ADC) and fractional anisotropy (FA) images can...
Source: BMC Medical Imaging - Category: Radiology Authors: Tags: Research article Source Type: research
ConclusionsIncidence and prevalence of these rare brain and other CNS tumor histologies have not been previously reported. Along with survival, these data provide a statistical foundation to understand the impact of these cancers and provide important disease-specific data for the design of prospective clinical trials.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research
Source: Clinical Trials And Noteworthy Treatments For Brain Tumors - Category: Cancer & Oncology Source Type: clinical trials
Chow Peter D. Chang Radiographic assessment with magnetic resonance imaging (MRI) is widely used to characterize gliomas, which represent 80% of all primary malignant brain tumors. Unfortunately, glioma biology is marked by heterogeneous angiogenesis, cellular proliferation, cellular invasion, and apoptosis. This translates into varying degrees of enhancement, edema, and necrosis, making reliable imaging assessment challenging. Deep learning, a subset of machine learning artificial intelligence, has gained traction as a method, which has seen effective employment in solving image-based problems, including those in me...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
Conclusion: Precise and bloodless tumor resection under OCT image guidance is demonstrated in the murine xenograft brain cancer model. Tumor margins and vasculature are accurately made visible without need for exogenous contrast agents.
Source: Theranostics - Category: Molecular Biology Authors: Tags: Research Paper Source Type: research
Conclusion: SNHG5 gene was high-expressed in glioma, knockdown of SNHG5 inhibits malignant cellular phenotypes of glioma via Wnt/CTNNB1 signaling pathway.
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Research Paper Source Type: research
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