Prognostic markers at adolescence in patients requiring liver transplantation for biliary atresia in adulthood

Biliary atresia (BA) is an idiopathic neonatal cholangiopathy characterized by progressive inflammatory obliteration of the intrahepatic or extrahepatic bile ducts.1 The surgical procedure, Kasai portoenterostomy (KP), aims to restore bile flow, and alleviate jaundice. Liver transplantation (LT) is performed in cases where KP is unable to salvage the native liver, with complications including jaundice, cholangitis, portal hypertension (PHT) and/or synthetic failure.2 Five and 10-year UK native liver survival (NLS) rates in BA have been documented as 46% and 40%, respectively.

Source: Journal of Hepatology - March 11, 2019 Category: Gastroenterology Authors: Vandana Jain, Charlotte Burford, Emma C Alexander, Harry Sutton, Anil Dhawan, Deepak Joshi, Mark Davenport, Nigel Heaton, Nedim Hadzic, Marianne Samyn Tags: Research Article Source Type: research