Vitamin D3 enhances the response to cisplatin in bladder cancer through VDR and TAp73 signaling crosstalk

ConclusionsOur data suggest that VitD deficiency could be a biomarker for poor response to cisplatin, and pretreating with VitD can increase the apoptotic response to cisplatin through VDR and TAp73 signaling crosstalk.

Source: Cancer Medicine - April 9, 2019 Category: Cancer & Oncology Authors: Brittany L. Bunch, Yingyu Ma, Kristopher Attwood, Lauren Amable, Wei Luo, Carl Morrison, Khurshid A. Guru, Anna Woloszynska ‐Read, Pamela A. Hershberger, Donald L. Trump, Candace S. Johnson Tags: ORIGINAL RESEARCH Source Type: research