IVF linked to slight increased childhood cancer risk

Children born through IVF have slight increased risk of certain childhood cancers during first decade of life, study finds Related items fromOnMedica Infertility much more likely after childhood cancer Higher heart risk for survivors of childhood cancer One in 10 children in phase I cancer trials respond to drugs Foetal alcohol syndrome must be better recognised Review reveals young cancer patients are put at risk
Source: OnMedica Latest News - Category: UK Health Source Type: news

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CONCLUSION: These findings indicate increased resistance of E. coli to ciprofloxacin in comparison with prior studies. Further research in this field will increase our knowledge and more effective exposure to the antibiotic resistance of the pathogenic microorganisms. PMID: 31198116 [PubMed - as supplied by publisher]
Source: Recent Patents on Anti-Infective Drug Discovery - Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research
CONCLUSIONS: During antihypertensive treatment, several dermatological reactions may occur. Clinicians should inform their patients of the increased risk of cutaneous lesions associated with the use of these drugs, and perform periodic examination of the skin. PMID: 31195782 [PubMed - as supplied by publisher]
Source: Giornale Italiano di Dermatologia e Venereologia - Category: Dermatology Tags: G Ital Dermatol Venereol Source Type: research
CONCLUSIONS: Our intervention was effective, by significantly improving the participants' knowledge and by inducing significant behavioral changes. Improving the formulation of alcoholic hand rubs may be a key factor to encourage their use. Coexisting non-occupational risk behaviors are just as important in the prevention of CHE. PMID: 31195780 [PubMed - as supplied by publisher]
Source: Giornale Italiano di Dermatologia e Venereologia - Category: Dermatology Tags: G Ital Dermatol Venereol Source Type: research
In this study, MCF-7 and T47D cells were treated with inhibitors of 17β-HSD1, 17β-HSD7, aromatase or steroid sulfatase (STS), then mRNA levels of 17β-HSD7, STS, 11β-HSD 2, estrogen receptors α (ERα) and androgen receptor (AR) were determined by Q-PCR. ER negative cell line MDA-MB-231 was used as a negative control. Our results demonstrate that 17β-HSD7, STS and 11β-HSD2 are all regulated by the same estrogen estradiol via ERα. When the gene of ERα (ESR1) was knocked down, there was no longer significant mutual regulation of these enzymes.Our results demonstrate that imp...
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
Preterm birth could double risk of kidney disease into mid-adulthood Related items fromOnMedica Infertility much more likely after childhood cancer Foetal alcohol syndrome must be better recognised Teens more likely to have an abortion if their mother did Stillbirth risk doubled in women sleeping on their back Doctors should regard FGM as child abuse
Source: OnMedica Latest News - Category: UK Health Source Type: news
In this study, a link between mitochondrial changes and infant temperament has also been suggested. Maternal psychosocial stress and lifetime trauma have been associated with decreased mitochondrial DNA copy number in the placenta (115, 116).IndividualityChronic stress links changes in the epigenetic landscape with health conditions (117). Different cell types are characterized by distinct patterns of gene expression due to developmental, environmental, physiological, and pathological reasons (117). Epigenetic mechanisms affect gene function in a dynamic way as a result of different environmental exposures during fetal dev...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
ConclusionsPerinatal and early-life risk factors, and specifically indicators of brain trauma, exposure to toxic agents and immune system maturation, might be involved in the pathogenesis of childhood brain tumors. Larger studies should aim to replicate our findings and examine associations with tumor subtypes.
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research
WebMD wasn't a research option when Ivy Brown was diagnosed with Hodgkin's lymphoma in 1974, so her mother looked up her 12-year-old daughter's condition the old-fashioned way, in a hardcover medical volume. "It just said 'fatal,'" Brown explained. Having moved the family to London a month earlier, Brown's parents were still trying to liaise with her pediatrician in the U.S. "My father told me recently that he was sleeping with the phone on his stomach because of the time change," she said. "They were as scared as you can be when you have a child who you think you might lose," Brown explained....
Source: Science - The Huffington Post - Category: Science Source Type: news
ConclusionWe hardly need more evidence to show smoking is bad for our health, but the suggestion that it may slightly increase the risk of an early menopause and chances of having problems getting pregnant could be important to some women. More surprising is that high levels of secondhand smoke exposure may also have a similar effect.This is a big study with a lot of detailed information about smoking and fertility. But it has some important limitations. It uses quite old data taken from a study of women who were in middle age in the 1990s. Smoking habits have changed a lot in the last 20 years, not only for active smoking...
Source: NHS News Feed - Category: Consumer Health News Tags: Heart/lungs Older people Pregnancy/child Source Type: news
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Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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