A Novel Synthetic Compound, Bismuth Zinc Citrate, Could Potentially Reduce Cisplatin-Induced Toxicity Without Compromising the Anticancer Effect Through Enhanced Expression of Antioxidant Protein.

In conclusion, pretreatment of BiZn decreased cisplatin-induced renal toxicity without affecting its antitumor activity. BiZn-induced antioxidant proteins MT and GSH may contribute to the renal protection effect. PMID: 30921749 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30921749?dopt=Abstract

Source: Translational Oncology - March 24, 2019 Category: Cancer & Oncology Authors: Chan S, Wang R, Man K, Nicholls J, Li H, Sun H, Chan GC Tags: Transl Oncol Source Type: research