Long noncoding RNA Xist predicts the presence of lymph node metastases in human esophageal squamous cell carcinoma.

Long noncoding RNA Xist predicts the presence of lymph node metastases in human esophageal squamous cell carcinoma. Br J Biomed Sci. 2019 Mar 18; Authors: Li J, He D PMID: 30883269 [PubMed - as supplied by publisher]
Source: British Journal of Biomedical Science - Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

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Source: OncoTargets and Therapy - Category: Cancer & Oncology Tags: OncoTargets and Therapy Source Type: research
Conclusions: The ADC 3D texture feature can be used as a useful biomarker to predict the survival of ESCC patients undergoing CRT. Combining ADC 3D texture features with conventional prognostic factors can generate reliable survival prediction models.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Computed tomography (CT) is commonly used in all stages of oesophageal squamous cell carcinoma (SCC) management. Compared to basic CT features, CT radiomic features can objectively obtain more information abou...
Source: Cancer Imaging - Category: Radiology Authors: Tags: Research article Source Type: research
Abstract PURPOSE: To examine whether submucosal saline injection (SSI) can improve traditional endoscopic ultrasound's (EUS) accuracy in distinguishing between T1a and T1b stage esophageal squamous cell carcinoma (ESCC). EXPERIMENTAL DESIGN: 180 T1N0M0 stage ESCC patients aged 18-85 years old were enrolled between February 14, 2012 to June 4, 2018 at Sun Yat-sen University Cancer Center in China. They were randomly assigned (1:1) to receive either EUS examination after 3-5 ml submucosal saline injection (SSI) or EUS only examination. All the patients were referred to thoracic surgeons to receive endoscopic re...
Source: Clinical Cancer Research - Category: Cancer & Oncology Authors: Tags: Clin Cancer Res Source Type: research
Future Oncology, Ahead of Print.
Source: Future Oncology - Category: Cancer & Oncology Authors: Source Type: research
This study aimed to evaluate the value of palliative resection or radiation of primary tumor for metastatic esophageal cancer using the Surveillance, Epidemiology, and End Results database. Additionally, we constructed prognostic nomograms for both preoperative and postoperative risk factors. We found that palliative resection or radiation could improve the survival of such patients, across both squamous cell carcinoma and adenocarcinoma. AbstractPurposeWe aimed to explore the value of palliative resection or radiation of primary tumor for metastatic esophageal cancer (EC) patients.MethodsSurveillance, Epidemiology, and En...
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
Authors: Zong MZ, Feng WT, Du N, Yu XJ, Yu WY Abstract OBJECTIVE: Recent studies have suggested that long noncoding RNAs (lncRNAs) are involved in various tumors. The present research was designed to examine the prognostic values of a newly identified lncRNA, lncRNA LEF1-AS1 (LEF1-AS1), in esophageal squamous cell carcinoma (ESCC). PATIENTS AND METHODS: The relative levels of LEF1-AS1 in ESCC tissues and normal esophageal tissues were examined by applying quantitative Real Time-Polymerase Chain Reaction (qRT-PCR). The relations between LEF1-AS1 expressions and clinical factors were analyzed by conducting the Ch...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
ConclusionsThe histogram parameters ofKtrans are useful in the assessment and prediction of the chemoradiotherapy response in patients with advanced esophageal squamous cell carcinoma. DCE-MRI could serve as an adjunctive imaging technique for treatment planning.
Source: La Radiologia Medica - Category: Radiology Source Type: research
Conclusion: IMRT-based CCRT resulted in higher survival rates in patients with advanced clinical stages of TESCC (i.e., IIIA–IIIC), namely, clinical T3, clinical T4, or lymph node involvement.
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
ConclusionAngiogenesis at the early stage of ESCC progression is configured by the balance between accelerator (angiogenic factors from both cancer cells and SMCs) and brake (angiogenic inhibitor) factors.
Source: Esophagus - Category: Gastroenterology Source Type: research
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