Enteral Versus Parenteral Nutrition: Use in Adult Patients Undergoing Hematopoietic Stem Cell Transplantation.

Enteral Versus Parenteral Nutrition: Use in Adult Patients Undergoing Hematopoietic Stem Cell Transplantation. Clin J Oncol Nurs. 2019 Apr 01;23(2):173-179 Authors: Reese MK, Hewlings S Abstract BACKGROUND: Pretransplantation chemotherapy and side effects of transplantation can cause reduced oral intake, contributing to malnutrition. OBJECTIVES: The aim was to evaluate the current evidence comparing enteral nutrition (EN) to parenteral nutrition in the adult hematopoietic stem cell transplantation (HSCT) population. METHODS: A systematic review was conducted in PubMed/MEDLINE®, CINAHL® Plus With Full Text (EBSCO), and Cochrane Library and produced 238 articles. Four articles met inclusion criteria. FINDINGS: Three studies were observational; one was a randomized trial that ended prematurely. Outcomes included tolerance of EN, incidences of graft-versus-host disease (GVHD), rate of infection, and mortality. This limited information suggests that EN may have a protective mechanism against advanced stages of GVHD and contribute to decreased risk of infection-related death. PMID: 30880810 [PubMed - in process]
Source: Clinical Journal of Oncology Nursing - Category: Nursing Authors: Tags: Clin J Oncol Nurs Source Type: research