[Cardiovascular drugs and renal function: Pitfall of renal adaptation].

CONCLUSION: The privileged use of Cockcroft and Gault formula for dose adjustment, as recommended by the Haute Autoritéde santé, does not seem to be justified. An overhaul of recommendations for pharmacokinetic studies and renal function assessment methods for dose adjustments appears necessary. PMID: 30827822 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30827822?dopt=Abstract

Source: Nephrologie and Therapeutique - February 27, 2019 Category: Urology & Nephrology Authors: Keller N, Ruppert M, Fourtage M, Hannedouche T Tags: Nephrol Ther Source Type: research