Prevalence, characteristics and antimicrobial susceptibility patterns of Clostridium difficile isolated from hospitals in Iran

ConclusionsThis is the first report of the isolation of C. difficile from different governmental hospitals of Iran and indicates that CDI might be an important nosocomial infection in different hospital wards. Moreover, this study provides a good comprehensive picture of the MDR phenotype characteristics of C. difficile isolates in Iran.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research

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Publication date: 25 March 2020Source: Journal of Ethnopharmacology, Volume 250Author(s): Rui Zheng, Liyuan Tao, Joey S.W. Kwong, Changming Zhong, Chengyu Li, Shiqi Chen, Yang Sun, Xiaoyu Zhang, Hongcai ShangAbstractEthnopharmacological relevanceXiyanping injection (XYP), extraction of Andrographis paniculate (Andrographis paniculata (Burm. f.) Nees, chuan xin lian), is a Chinese patent medicine approved to treat bronchitis in China. In 2017, safety incidents associated with treatment of XYP began to emerge throughout China. However, the risk factors of severity of adverse reactions by XYP remain uncertain.Aim of the study...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
CONCLUSION: FMT seems to be a promising and safe therapy in the management of UC. Further research, with larger cohorts, will be needed to confirm this and to determine the optimal FMT procedure. PMID: 31950808 [PubMed - in process]
Source: Acta Gastro-Enterologica Belgica - Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research
Publication date: Available online 17 January 2020Source: Journal of Clinical NeuroscienceAuthor(s): Bahareh Rabbani, Mohammad Kazem Bakhshandeh, Mohammad Reza Navaeifar, Ali Abbaskhanian, Mahdieh Soveizi, Shahpour Geravandpoor, Nejat MahdiehAbstractBrown-Vialetto-Van Laere syndrome, a rare neurological disorder is due to SLC52A3 mutations. Here, the SLC52A3 protein and its mutations are in silico structurally and functionally analyzed among all the reported patients and a novel mutation is also reported.After clinical evaluations, SLC52A3 gene was sequenced and segregation analysis of the mutations was also checked. A com...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
AbstractThe present study evaluated adherence to antiemetic guidelines for prevention and treatment of chemotherapy-induced nausea and vomiting (CINV) in four tertiary university teaching hospitals in Tehran. This prospective observational study enrolled 382 adult patients on chemotherapy at oncology centers affiliated to medical universities located in Tehran. Patients were followed up during their chemotherapy cycles. Risk factors related to CINV were evaluated, and information on antiemetic prescribing patterns was gathered using direct interview and patient medical records. Guideline adherence was found to be low; howe...
Source: Journal of Cancer Education - Category: Cancer & Oncology Source Type: research
han Wouters Mycobacterium tuberculosis is still the deadliest bacterial pathogen worldwide and the increasing number of multidrug-resistant tuberculosis cases further complicates this global health issue. M. tuberculosis phosphoserine phosphatase SerB2 is a promising target for drug design. Besides being a key essential metabolic enzyme of the pathogen’s serine pathway, it appears to be involved in immune evasion mechanisms. In this work, a malachite green-based phosphatase assay has been used to screen 122 compounds from an internal chemolibrary. Trisubstituted harmine derivatives were found among the best h...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Publication date: Available online 17 January 2020Source: Microchemical JournalAuthor(s): Zahra Rahimi Nadi, Taghi Zahraei Salehi, Iradj Ashrafi Tamai, Abbas Rahimi foroushani, Mika Sillanpaa, Mohammad Mehdi Soltan DallalAbstractSalmonella is one of the major causes of foodborne outbreaks and numerous studies have reported the presence of its serovars in foodborne outbreaks. Identification of the most prevalent serovars, common polluted food types and attention to the antibiotic resistance of its serovars, are therefore key factors in the prevention and control of salmonellosis. The aim of this study is thus isolation of t...
Source: Microchemical Journal - Category: Chemistry Source Type: research
Publication date: Available online 17 January 2020Source: Chemical Engineering JournalAuthor(s): Yong Guo, Congcong Yan, Peifang Wang, Lei Rao, Chao WangAbstractA series of carbon-doped boron nitride (BCN) are synthesized via oxygen-limited method, in which BCN-0.6 has the best adsorption quantity for tetracycline (TC). BCN-0.6 can capture protons and increase the pH of TC solution from 3.80 to 7.87, which makes that TC changes to negative state (pH 7.87) from neutral state (pH 3.80). BCN-0.6 exists in protonated form in solution. TC adsorption quantity by BCN-0.6 in pH 7.87 is higher than that in pH 3.8 (76.74 mg·g...
Source: Chemical Engineering Journal - Category: Chemistry Source Type: research
Publication date: Available online 16 January 2020Source: Chemical Engineering JournalAuthor(s): Yanhong Chao, Jian Zhang, Hongping Li, Peiwen Wu, Xiaowei Li, Honghong Chang, Jing He, Haofeng Wu, Huaming Li, Wenshuai ZhuAbstractEngineering structure defects in boron nitride for enhancing adsorption performance is imperative for the rational design of a high-efficient adsorbent. Herein, boron nitride nanosheets (BNNSs) with nitrogen defects were in situ synthesized via a one-step alkali-assisted strategy. N-defects in BNNSs framework tune the morphological and electronic structure of the nanomaterial, strengthening the inte...
Source: Chemical Engineering Journal - Category: Chemistry Source Type: research
Publication date: Available online 18 January 2020Source: American Journal of Infection ControlAuthor(s): Catherine Zaw, Divy Mehra
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
ConclusionLAMA4 was up-regulated by AR through directly binding to its specific promoter region, and was associated with the enhanced cisplatin resistance in GC, which provided new mechanism and better understandings for treating drug-resistant GC.
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
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