Increased splenic human CD4+:CD8+ T cell ratios, serum human interferon- γ and intestinal human interleukin-17 are associated with clinical graft-versus-host disease in humanized mice.
This study also provides further insights into GVHD development which may be relevant to human HSCT recipients.
PMID: 30743002 [PubMed - as supplied by publisher]
Source: Transplant Immunology - Category: Transplant Surgery Authors: Geraghty NJ, Belfiore L, Adhikary SR, Alexander SI, Sluyter R, Watson D Tags: Transpl Immunol Source Type: research
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