Microvascular density, macrophages, and mast cells in human clear cell renal carcinoma with and without bevacizumab treatment.

CONCLUSIONS: It follows that the antiangiogenic activity of bevacizumab may be due to a direct effect on angiogenic cytokines released by tumor cells and an indirect effect on the release of pro-angiogenic factors by inflammatory stromal cells.
PMID: 30738745 [PubMed - as supplied by publisher]

Source: Urologic Oncology - February 6, 2019 Category: Urology & Nephrology Authors: Tamma R, Rutigliano M, Lucarelli G, Annese T, Ruggieri S, Cascardi E, Napoli A, Battaglia M, Ribatti D Tags: Urol Oncol Source Type: research