Which antimuscarinic agents used in the treatment of overactive bladder increase heart rate? a prospective randomized clinical trial

ConclusionsOur results showed that heart rate significantly increased in OAB patients treated with non-selective antimuscarinic drugs. Trospium chloride, tolterodine tartrate, fesoterodine fumarate and propiverine hydrochloride seem to have the most unfavorable properties with regard to increased heart rate side effect when compared to the other antimuscarinic drugs (darifenacin hydrobromide, solifenacin succinate and oxybutynin hydrochloride).
Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research