Trichostatin A (TSA) levels in response to treatment of rainbow trout with gamma-irradiated trophonts against Ichthyophthirius multifiliis

In this study, TSA levels induced by gamma-irradiated trophonts and alginate/calcium phosphate nanoparticles were measured after 30  days following treatment againstI.multifiliis in spleen, kidney, and liver tissues of rainbow trout. This sounds like TSA is an anti-parasitic enzyme that can increase in spleen, kidney, and liver tissues following treatment of rainbow trout againstI.multifiliis (P <  0.05). Moreover, the results obtained from this study showed that the TSA activity level is tissue-dependent. The highest significance levels for TSA activity were found in spleen tissue of treated and healthy groups compared with the levels of the both liver and kidney tissues (P <  0.05).
Source: Comparative Clinical Pathology - Category: Pathology Source Type: research