Ivacaftor, a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator, Enhances Ciprofloxacin Activity Against Pseudomonas aeruginosa.

CONCLUSION: Ivacaftor enhanced ciprofloxacin's antimicrobial activity against P. aeruginosa. Further studies evaluating the efficacy of ivacaftor/ciprofloxacin combination for P. aeruginosa for CF CRS are warranted.
PMID: 30585080 [PubMed - as supplied by publisher]

Source: American Journal of Rhinology and Allergy - December 25, 2018 Category: ENT & OMF Authors: Cho DY, Lim DJ, Mackey C, Skinner D, Zhang S, McCormick J, Woodworth BA Tags: Am J Rhinol Allergy Source Type: research