Abstract 4124: Ovarian cancer survival by tumor subtype

Conclusion: Regardless of how subtype was defined, high grade, invasive serous tumors had worse survival compared to other tumor subtypes. This underscores the need for prevention and treatment targeted at these aggressive tumors.
canres;74/19_Supplement/4124/table1T1
Table.
Associations between tumor subtype and overall survival Subtype
Deaths/Cases
Median Survival (years)
HR (95% CI) Histology Serous invasive
654/968
3.2
1.00 (ref.) Serous borderline
25/250
10.1
0.35 (0.18-0.67) Mucinous
36/242
7.1
0.38 (0.25-0.58) Endometrioid
68/331
4.7
0.28 (0.21-0.37) Clear cell
29/116
3.4
0.30 (0.21-0.44) Dominance Non-dominant
268/385
3.3
1.00 (ref.) Dominant
162/603
4.0
0.38 (0.31-0.47) Pathway Type III
596/856
3.2
1.00 (ref.) Type II
97/447
4.0
0.23 (0.18-0.29) Type I
60/291
5.7
0.21 (0.16-0.28) Citation Format: Elizabeth M. Poole, Daniel W. Cramer, Allison F. Vitonis, Kathryn L. Terry. Ovarian cancer survival by tumor subtype. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 4124. doi:10.1158/1538-7445.AM2014-4124

Source: Cancer Research - September 30, 2014 Category: Cancer & Oncology Authors: Poole, E. M., Cramer, D. W., Vitonis, A. F., Terry, K. L. Tags: Epidemiology Source Type: research