Lymphadenopathy in a TB-Endemic Region: Employing Focused Techniques in a Rapid Access Lymph Node Biopsy Clinic

ConclusionThe Ultra shows promising sensitivity and should routinely be performed for both HIV+ and -patients at the first visit in the investigation of unexplained lymphadenopathy in a TB-endemic region. If the Ultra is negative, a core-needle biopsy is the most appropriate next investigation. In a TB-endemic region, FNAC should be reserved for patients >50 years who are HIV negative. There is no role for empiric TB treatment for patients with peripheral lymphadenopathy in the era of new TB diagnostic tests, and the application of these investigations with early biopsy for patients with negative TB tests will result in earlier detection of lymphoma.DisclosuresNo relevant conflicts of interest to declare.

Source: Blood - November 21, 2018 Category: Hematology Authors: Antel, K. R., Verburgh, E., Louw, V. J., Oosthuizen, J., Malherbe, F., Gary, M., Nicol, M. Tags: 622. Lymphoma Biology-Non-Genetic Studies Source Type: research