Preliminary results of a french pilot trial of lung cancer screening by low dose CT scan in the department of the Somme (DKP80)

This study is managed by the departmental cancer screening agency (ADEMA80).All general practitioners, pulmonologists and radiologists from Somme were solicited by mail to participate in this study.218 general practitioners, 17 pneumologists and 28 radiologists accepted to participate in this study. 998 subjects were recruited in 20 months and 663 scans were performed representing a participation rate of 66%. Screening was negative in 608 cases (92%), positive in 42 (6.3%) and indeterminate in 13 (1.9%).17 cancers were detected. There were 10 adenocarcinomas,2 squamous cell carcinomas, 1 carcinoid tumor, 2 small cell carcinomas and 2 unknown. There were 9 Stage IA (53%).The lung cancer detection rate is 2.5% and the Positive Predictive Value is 40%.This study demonstrates the feasibility and effectiveness at a regional level of organized and structured screening of lung cancer by low dose CT scan in France.

Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Leleu, O., Hoguet, E., Clarot, C., Baud, M., Barras, E., Petigny, V., Benoit, N., Auquier, M., Chauffert, B., Berna, P., Jounieaux, V. Tags: Lung Cancer Source Type: research