Imaging tryptophan uptake with positron emission tomography in glioblastoma patients treated with indoximod

ConclusionsHere, we have validated the ability to use PET of the Trp probe, AMT, for use in visualizing and quantifying intratumoral Trp uptake in GBM patients treated with an IDO1 pathway inhibitor. These data serve as rationale to utilize AMT-PET imaging in the future evaluation of GBM patients treated with IDO1 enzyme inhibitors.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research