The Landscape of Protein Tyrosine Phosphatase (Shp2) and Cancer.

Conclusion: The current study was designed to focus on the allosteric regulation (autoinhibition) of the of Shp2 protein. Subsequently, it will cover the last 10-year recap of Shp2 protein, their role in cancer, and regulation in numerous ways (allosteric regulation).
PMID: 30398108 [PubMed - as supplied by publisher]

Source: Current Pharmaceutical Design - November 5, 2018 Category: Drugs & Pharmacology Authors: Rehman AU, Rehman MU, Tahir KM, Saud S, Liu H, Song D, Sultana P, Wadood A, Chen HF Tags: Curr Pharm Des Source Type: research