p107 Deficiency Increases Energy Expenditure by Inducing Brown ‐fat Thermogenesis and Browning of White Adipose Tissue

ConclusionThese data allowed us to unmask a mechanism by which a KO of p107 prevents diet ‐induced obesity by increasing energy expenditure via increased thermogenesis in BAT and browning of WAT, indicating the relevance of p107 as a modulator of metabolic activity of both brown and white adipocytes. Therefore, it could be targeted for the development of new therapies to ameliorate the metabolic syndrome.This article is protected by copyright. All rights reserved

Source: Molecular Nutrition and Food Research - November 1, 2018 Category: Food Science Authors: Juan Cunarro, Xabier Buque, Sabela Casado, Javier Lugilde, Anxo Vidal, Alfonso Mora, Guadalupe Sabio, Rub én Nogueiras, Patricia Aspichueta, Carlos Diéguez, Sulay Tovar Tags: Research Article Source Type: research