Resveratrol Activated Sonic Hedgehog Signaling to Enhance Viability of NIH3T3 Cells < b > < i > in Vitro < /i > < /b > via Regulation of Sirt1

Conclusion: We indicate in the first time that it may be mediated by Sirt1 for resveratrol activating the Shh signaling to enhance viability of NIH3T3 cells, and Sirt1 may be a regulator for upstream of the Shh signaling pathway.This study provides a basis for further investigating effects and mechanism of resveratrol during the formation of fibrous scar after brain or spinal cord injury.Cell Physiol Biochem 2018;50:1346 –1360
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research