Arrhythmic genotypes in familial dilated cardiomyopathy: implications for genetic testing and clinical management

Cardiac arrhythmias are frequently seen in patients with dilated cardiomyopathy (DCM) and can precipitate heart failure and death. In patients with non-ischaemic DCM, evidence for the benefit of an implantable cardioverter-defibrillator (ICD) for primary prevention of sudden cardiac death has recently been questioned. Algorithms devised to identify high-risk individuals who might benefit most from ICD implantation have focussed on clinical criteria with little attention paid to the underlying aetiology of DCM.

Source: Heart, Lung and Circulation - October 10, 2018 Category: Cardiology Authors: Stacey Peters, Saurabh Kumar, Perry Elliott, Jonathan M. Kalman, Diane Fatkin Source Type: research