Clinical characteristics of obstructive sleep apnea in bipolar disorders.

Worldwide, approximately 1% to 4% of people suffer from bipolar disorder (BD). BD is a severe mental disorder ranking as the fourth most important contributor to the global disease burden among psychiatric, neurological and substance-use disorders (Collins et al., 2011; Merikangas et al., 2007). Whereas BD has traditionally been defined by recurrences of manic and depressive episodes, it is now recognized that BD patients also present with persistent abnormalities between mood episodes (such as cognitive deficits, cardio-vascular diseases, altered sleep homeostasis and circadian dysregulation), leading to conceptualizations of BD as a chronic and multisystem disorder (Leboyer et al., 2012).
Source: Journal of Affective Disorders - Category: Neurology Authors: Tags: Research paper Source Type: research