Nose to brain delivery of galantamine loaded nanoparticles: In-vivo pharmacodynamic and biochemical study in mice.

CONCLUSION: Significant recovery in amnesia induced mice model by intranasal administration of galantamine loaded thiolated chitosan nanoparticles establish the relevance of nose to brain delivery over the conventional oral therapies for the treatment of alzheimer's disease. PMID: 30289074 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30289074?dopt=Abstract

Source: Current Drug Delivery - October 3, 2018 Category: Drugs & Pharmacology Authors: Jha S, Singh SK, Mishra DN Tags: Curr Drug Deliv Source Type: research