Characterization of point mutations in domain V of 23S rRNA gene of clinical strains of Helicobacter pylori and clarithromycin-resistant phenotype in central Vietnam

ConclusionsThere was a diversity of point mutations of 23S rRNA domain V of clinical strains of H. pylori. The rate of phenotypic CLA-resistant H. pylori is remarkably increasing in central Vietnam. Further research is necessary to clarify the role of the combination of 23S rRNA domain V mutations in the molecular mechanism of clarithromycin-resistance.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research