Clinical and radiological characteristics and predictors of outcome of cerebral venous sinus thrombosis, a hospital-based study

AbstractCerebral venous sinus thrombosis is an uncommon cause of stroke, which is more prevalent in Iran and the Middle East. We aimed to assess the etiology, radiologic, and clinical manifestations of cerebral venous sinus thrombosis, specifically the predictors of patients ’ outcome in Namazi hospital, Shiraz, Iran. In this retrospective study, we included all adult patients with the diagnosis of cerebral venous sinus thrombosis, who were admitted in hospital, from 2012 to 2016. Demographic data, radiologic findings, clinical presentation, risk factors, treatment, a nd outcome according to modified Rankin Scale (mRS) on discharge were assessed and the factors associated with hospital fatality and poor outcome (mRS >  2) were investigated through univariable and multivariable analyses. Adjusted odds ratio (OR), 95% confidence interval (CI), andp values were reported. Among 174 patients, 128 (73.6%) were female. The mean age was 37.8  ± 11.2. Total of 39 patients (22.4%) had poor discharge outcome and nine patients died in hospital. Older age (OR = 1.041, CI = 1.000–1.08), decreased level of consciousness (OR = 5.46, CI = 2.17–13.72), focal neurologic deficit (OR = 5.63, CI = 2.14–14.77), and e xpansion of intracranial hemorrhage (ICH) (OR = 9.13, CI = 1.96–42.64) were predictors of poor outcome according to the logistic regression model. Older age (p = 0.02), focal neurologic deficit (p = 0.005), deep venous syste...
Source: Acta Neurologica Belgica - Category: Neurology Source Type: research