[Role of p16(INK4A) in detection of human papillomavirus DNA and stratification of cancer-specific mortality on the basis of long term follow-up data of 34 patients with invasive penile cancer].

CONCLUSIONS:  In contrast to ISH and the examined histological criteria, p16INK4a allows a reasonable prediction of HPV status. Neither HPV DNA nor its surrogate markers independently impacted CSM. As urethral tumour invasion does not independently influence CSM, the recent pT classification can be considered useful for prognosis.
PMID: 30227445 [PubMed - as supplied by publisher]

Source: Aktuelle Urologie - September 18, 2018 Category: Urology & Nephrology Authors: Bründl J, Neppl C, Hommer T, Otto W, Breyer J, Brookman-May S, Weber F, Burger M, May M, Eichelberg C Tags: Aktuelle Urol Source Type: research