PINK1/Parkin-Mediated Mitophagy Promotes Resistance to Sonodynamic Therapy

Conclusion: Taken together, we conclude that ROS produced by 5-ALA-SDT could initiate PINK1/Parkin-mediated mitophagy which may exert a protective effect against 5-ALA-SDT-induced cell death in MCF-7 cells.Cell Physiol Biochem 2018;49:1825 –1839
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research