Progressive bone impairment with age and pubertal development in neurofibromatosis type I

ConclusionBone density impairment becomes more evident with growth and pubertal development in NF-1 patients, thus identifying childhood as the best time frame to introduce prevention strategies aiming at peak bone mass achievement. TBS and BS, providing bone DXA qualitative information, could be useful during longitudinal follow-up for better characterizing bone impairment in these patients.
Source: Archives of Orthopaedic and Trauma Surgery - Category: Orthopaedics Source Type: research