Ultrasound Shear Wave Elastography as a Measure of Porcine Hepatic Disease in Right Heart Dysfunction: A Pilot Study

Patients with congenital heart disease with a pressure-overloaded right ventricle can develop liver disease and would benefit from non-invasive diagnostic modalities such as ultrasound shear wave elastography (US SWE). We sought to investigate the ability of US SWE to measure dynamic changes in liver stiffness with an acute fluid bolus in an animal model. Three piglets underwent surgical intervention to create a pressure-overloaded right ventricle and, 12 wk later, underwent US SWE, both pre- and post-intravenous infusion of a saline bolus.

Source: Ultrasound in Medicine and Biology - August 18, 2018 Category: Radiology Authors: Jessie J. Hu, M. Yasir Qureshi, Matthew W. Urban, Rondell Graham, Meng Yin, Saji Oommen, Kimberly A. Holst, Sarah Edgerton, Luiz Vasconcelos, Ivan Nenadic, Frank Cetta, for the Wanek Program Pre-clinical Pipeline Tags: Technical Note Source Type: research