In vivo imaging of the immune response upon systemic RNA cancer vaccination by FDG-PET

ConclusionsOur preclinical results show rapid and transient vaccination-induced increase of FDG uptake within the spleen reflecting immune activation preceding T cell proliferation. FDG-PET/CT in patients is also capable to image this immune activation resulting in a new potential application of FDG-PET/CT to image immune processes in new immunological therapies.
Source: EJNMMI Research - Category: Radiology Source Type: research