Neurogranin and BACE1 in CSF as Potential Biomarkers Differentiating Depression with Cognitive Deficits from Early Alzheimer ’s Disease: A Pilot Study

Conclusion: The neurogranin/BACE1 ratio in CSF can distinguish between depression and AD among patients with similar cognitive deficits, along with the classic AD biomarkers. Further longitudinal studies are ongoing to identify which biomarkers have prognostic value.Dement Geriatr Cogn Disord Extra 2018;8:277 –289
Source: Dementia and Geriatric Cognitive Disorders Extra - Category: Geriatrics Source Type: research