Drug Use before and after Initiating Treatment with Acetylcholinesterase Inhibitors
Conclusion: Increased use of antidepressants and antipsychotics was observed both before and after initiation of AChEIs and may indicate that behavioral symptoms occur in a preclinical or early phase of Alzheimer ’s disease. The prescription pattern of analgesics with a low use of opioids may indicate an undertreatment of pain in people with dementia.Dement Geriatr Cogn Disord Extra 2019;9:196 –206 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - April 26, 2019 Category: Geriatrics Source Type: research

Erratum
Dement Geriatr Cogn Disord Extra 2019;9:195 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - April 18, 2019 Category: Geriatrics Source Type: research

Frailty in Older Adults with Mild Dementia: Dementia with Lewy Bodies and Alzheimer ’s Disease
Conclusion: Frailty was higher than expected in both types of dementia. The prevalence of frailty was higher in those with DLB compared to AD. This new finding underscores the need for a multi-systems approach in both dementias, with a particular focus on DLB.Dement Geriatr Cogn Disord Extra 2019;9:176 –183 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - April 15, 2019 Category: Geriatrics Source Type: research

Predicting Cognitive Decline and Dementia with the Newly Normed SKT Short Cognitive Performance Test
Conclusions: The newly normed SKT showed a high predictive validity for the onset of dementia.Dement Geriatr Cogn Disord Extra 2019;9:184 –193 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - April 15, 2019 Category: Geriatrics Source Type: research

Erratum
Dement Geriatr Cogn Disord Extra 2019;9:194 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - April 15, 2019 Category: Geriatrics Source Type: research

People with Dementia in Sub-Saharan Africa: From Support to Abuse by Caregivers: Results of EPIDEMCA-FU Program in Congo
Conclusion: Stigma, generated by social representations, can change the patient’s behavior and the one of informal caregivers, leading to time delay in the search for appropriate help.Dement Geriatr Cogn Disord Extra 2019;9:163 –175 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - April 3, 2019 Category: Geriatrics Source Type: research

Cerebrospinal Fluid Biomarkers for the Diagnosis of Prodromal Alzheimer ’s Disease in Amnestic Mild Cognitive Impairment
Conclusions: CSF biomarkers are very useful tools for the differential diagnosis of prodromal AD in aMCI patients. The concentration of CSF biomarkers is well correlated with the stages of the AD spectrum.Dement Geriatr Cogn Disord Extra 2019;9:100 –113 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - March 14, 2019 Category: Geriatrics Source Type: research

Novel Face-Name Paired Associate Learning and Famous Face Recognition in Mild Cognitive Impairment: A Neuropsychological and Brain Volumetric Study
Conclusions: Novel and semantically familiar face-name associative recalls are significantly impaired in MCI, and these potentially predate the MRI volumetric changes in MCI. Our findings expand the spectrum of recall deficits in MCI.Dement Geriatr Cogn Disord Extra 2019;9:114 –128 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - March 14, 2019 Category: Geriatrics Source Type: research

Impact of Physical Fitness on Cognitive Performance in Patients at a Memory Clinic
Conclusion: Low CRF and MF are associated with cognitive impairment. This applies even in 50- to 60-year-old nondemented subjects without marked physical morbidity. These findings support the potential usefulness of physical exercise for dementia prevention.Dement Geriatr Cogn Disord Extra 2019;9:129 –135 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - March 14, 2019 Category: Geriatrics Source Type: research

Language in Amnestic Mild Cognitive Impairment and Dementia of Alzheimer ’s Type: Quantitatively or Qualitatively Different?
Conclusion: Language tests provide an important contribution to the diagnostic process in their capacity to identify language impairments at an early stage. Understanding the nature of language decline is critically important to the intervention process as this information would inform cognitive intervention approaches aimed at promoting quality of life in people living with MCI and dementia.Dement Geriatr Cogn Disord Extra 2019;9:136 –151 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - March 14, 2019 Category: Geriatrics Source Type: research

Subjective Cognitive Decline in the Community Is Affected at Multiple Aspects of Mental Health and Life Quality: A Cross-Sectional Study of the Community Medicine of Keelung Chang Gung Memorial Hospital
Conclusions: Aging increased the SCD risk. People with SCD had suboptimal performance in mental health and life quality in addition to subjective cognition problems.Dement Geriatr Cogn Disord Extra 2019;9:152 –162 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - March 14, 2019 Category: Geriatrics Source Type: research

Effects of Music Therapy in Frail Elderlies: Controlled Crossover Study
Conclusions: MT may improve physical function, depressive mood, and quality of life in frail elderly individuals.Dement Geriatr Cogn Disord Extra 2019;9:87 –99 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - March 7, 2019 Category: Geriatrics Source Type: research

Long-Term Storage Effects on Stability of A β < sub > 1 –40 < /sub > , A β < sub > 1 –42 < /sub > , and Total Tau Proteins in Human Plasma Samples Measured with Immunomagnetic Reduction Assays
Conclusion: Although the measured concentrations of T-Tau in human plasma may alter during storage, the diagnostic utility of the results are only slightly affected when the product of A β1 –42 and T-Tau concentrations are used. The results show that the overall agreement between baseline and repeated measurements in the ability of discriminating NCs from aMCI/AD patients is higher than 80%.Dement Geriatr Cogn Disord Extra 2019;9:77 –86 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - February 12, 2019 Category: Geriatrics Source Type: research

Molecular Network Analysis of the Urinary Proteome of Alzheimer ’s Disease Patients
Conclusion: Our findings suggest that changes in the urinary proteome of AD patients reflect systemic changes related to AD pathophysiology.Dement Geriatr Cogn Disord Extra 2019;9:53 –65 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - February 8, 2019 Category: Geriatrics Source Type: research

Validation of the Malay Version of Addenbrooke ’s Cognitive Examination III in Detecting Mild Cognitive Impairment and Dementia
Conclusions: The Malay version of ACE-III demonstrated to be a reliable and valid screening tool for dementia.Dement Geriatr Cogn Disord Extra 2019;9:66 –76 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - February 8, 2019 Category: Geriatrics Source Type: research

How the Post-Fracture Rehabilitation Choice Affects Brain Function in Older People?
Conclusions: Cognitive function and antioxidant potential did not differ between the 2 types of rehabilitation. However, the impact on cerebral neuronal activity may have differed.Dement Geriatr Cogn Disord Extra 2019;9:34 –43 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - February 7, 2019 Category: Geriatrics Source Type: research

Optimal Cutoff Scores for Dementia and Mild Cognitive Impairment in the Brazilian Version of the Montreal Cognitive Assessment among the Elderly
Conclusions: MoCA-BR scores under 21 points (after adding 1 point to the elderly with ≤12 years of education) indicate a need to continue the diagnostic investigation with regular follow-ups.Dement Geriatr Cogn Disord Extra 2019;9:44 –52 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - February 7, 2019 Category: Geriatrics Source Type: research

Changes of Myelin Organization in Patients with Alzheimer ’s Disease Shown by q-Space Myelin Map Imaging
Conclusion: Our findings suggest that MM imaging could be a clinically proper modality to estimate the myelination changes in AD patients.Dement Geriatr Cogn Disord Extra 2019;9:24 –33 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - February 6, 2019 Category: Geriatrics Source Type: research

Cognitive Performance among Cognitively Healthy Adults Aged 30 –100 Years
Conclusions: When assessing cognition, age and education should be accounted for in more detail in research and clinical practice. Additionally, the cohort effect and its potential impact on the renewal cycle of future normative values for cognitive tests should be considered.Dement Geriatr Cogn Disord Extra 2019;9:11 –23 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - February 1, 2019 Category: Geriatrics Source Type: research

Smoking and Obesity as Risk Factors in Frontotemporal Dementia and Alzheimer ’s Disease: The HUNT Study
Conclusion: Our findings suggest that obesity is a shared risk factor for FTD and AD, while smoking plays various roles as a risk factor for FTD and AD.Dement Geriatr Cogn Disord Extra 2019;9:1 –10 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - January 13, 2019 Category: Geriatrics Source Type: research

The 12-Word Philadelphia Verbal Learning Test Performances in Older Adults: Brain MRI and Cerebrospinal Fluid Correlates and Regression-Based Normative Data
Conclusion: The PVLT appears sensitive to markers of neurodegeneration, including temporal regions affected by AD. Conversely, in cognitively normal older adults, PVLT performance seems to relate to white matter disease and axonal injury, perhaps reflecting non-AD pathways to cognitive change. Enhanced normative data enrich the clinical utility of this tool.Dement Geriatr Cogn Disord Extra 2018;8:476 –491 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - December 6, 2018 Category: Geriatrics Source Type: research

Can the Mixed Virtual Reality Simulator Into D ’mentia Enhance Empathy and Understanding and Decrease Burden in Informal Dementia Caregivers?
Conclusion: Caregivers indicated that the Into D ’mentia intervention improved their understanding of dementia, that they had learned to be more patient, to take things more slowly, and to focus on positive aspects of caregiving. However, no significant change was found on the variables assessed via the questionnaires. Future research can consid er enriching this intervention with other aspects such as more educational material, more simulations, and group sessions, tailored to the individual caregiver and his/her situation, and examine whether these new interventions yield change on questionnaires. These new, more p...
Source: Dementia and Geriatric Cognitive Disorders Extra - December 6, 2018 Category: Geriatrics Source Type: research

Neuropsychiatric Manifestations of Cognitively Advanced Idiopathic Normal Pressure Hydrocephalus
Conclusions: It can be concluded that neurobehavioral abnormalities are common in patients with cognitively advanced normal pressure hydrocephalus. However, the intensity of involvement appeared less when compared to Alzheimer ’s disease. Apathy appears to be the most common impairment.Dement Geriatr Cogn Disord Extra 2018;8:467 –475 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - December 6, 2018 Category: Geriatrics Source Type: research

Lifestyle Factors Are Important Contributors to Subjective Memory Complaints among Patients without Objective Memory Impairment or Positive Neurochemical Biomarkers for Alzheimer ’s Disease
Conclusions: Lifestyle factors including sleep and stress are useful in characterizing subjective memory complaints from objective problems. Inclusion of these variables could potentially improve health care utilization efficiency and guide interventions.Dement Geriatr Cogn Disord Extra 2018;8:439 –452 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - November 28, 2018 Category: Geriatrics Source Type: research

Quantitative Electroencephalography Analyzed by Statistical Pattern Recognition as a Diagnostic and Prognostic Tool in Mild Cognitive Impairment: Results from a Nordic Multicenter Cohort Study
Conclusion: The diagnostic and prognostic abilities of qEEG were low. The SPR method was superior to the visual EEG analysis. The qEEG method correlates well to CSF AD biomarkers, suggesting association with pathology in AD.Dement Geriatr Cogn Disord Extra 2018;8:426 –438 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - November 27, 2018 Category: Geriatrics Source Type: research

Anxiety and Depression as Risk Factors in Frontotemporal Dementia and Alzheimer ’s Disease: The HUNT Study
Conclusion: Our study findings suggest that anxiety and depression may play different roles as risk factors for FTD and AD.Dement Geriatr Cogn Disord Extra 2018;8:414 –425 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - November 22, 2018 Category: Geriatrics Source Type: research

Demographics, Clinical Characteristics, and Therapeutic Approaches among Older Adults Referred to Mobile Psychiatric Crisis Intervention Teams: A Retrospective Study
Conclusion: Appropriate responses by dual nurse-psychiatrist teams using crisis-oriented nonpharmacological and pharmacological interventions decreased hospitalization.Dement Geriatr Cogn Disord Extra 2018;8:402 –413 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - October 25, 2018 Category: Geriatrics Source Type: research

A Longitudinal Study of Peripheral and Central Auditory Function in Alzheimer ’s Disease and in Mild Cognitive Impairment
Conclusions: Our study indicates that DDT performance reflects an ongoing process resulting in dementia.Dement Geriatr Cogn Disord Extra 2018;8:393 –401 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - October 24, 2018 Category: Geriatrics Source Type: research

Current Perspectives and Mechanisms of Relationship between Intestinal Microbiota Dysfunction and Dementia: A Review
Background: Accumulating data suggest a crucial role of the intestinal microbiota in the development and progression of neurodegenerative diseases. More recently, emerging reports have revealed an association between intestinal microbiota dysfunctions and dementia, a debilitating multifactorial disorder, characterized by progressive deterioration of cognition and behavior that interferes with the social and professional life of the sufferer. However, the mechanisms of this association are not fully understood.Summary: In this review, I discuss recent data that suggest mechanisms of cross-talk between intestinal microbiota ...
Source: Dementia and Geriatric Cognitive Disorders Extra - October 18, 2018 Category: Geriatrics Source Type: research

Psychometric Properties of a Flanker Task in a Sample of Patients with Dementia: A Pilot Study
Conclusion: The Flanker task appears to be feasible, and a reliable and valid measure of selective attention. Although the test-retest reliability for the Flanker RT interference measure was fair, future studies need to confirm its validity to measure inhibitory control in patients with dementia.Dement Geriatr Cogn Disord Extra 2018;8:382 –392 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - October 18, 2018 Category: Geriatrics Source Type: research

Older Adults ’ Attitudes towards Cognitive Testing: Moving towards Person-Centeredness
Conclusion: Older adults have preferences for cognitive tests, especially with delivery of results.Dement Geriatr Cogn Disord Extra 2018;8:348 –359 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - October 9, 2018 Category: Geriatrics Source Type: research

The Impact of Using Measurements of Electrodermal Activity in the Assessment of Problematic Behaviour in Dementia
Conclusion: With the addition of information from the sensor, nursing staff could target causes and triggers in a better way, making care interventions more specific and directed towards certain times throughout the day to prevent patterns of problematic behaviours.Dement Geriatr Cogn Disord Extra 2018;8:333 –347 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - October 9, 2018 Category: Geriatrics Source Type: research

Number Needed to Diagnose, Predict, or Misdiagnose: Useful Metrics for Non-Canonical Signs of Cognitive Status?
Conclusion: NND, NNP, and NNM may be useful, intuitive, metrics in assessing the utility of diagnostic tests in day-to-day clinical practice. A ratio of NNM to either NND or NNP, termed the likelihood to diagnose or misdiagnose, may clarify the utility or inutility of diagnostic tests.Dement Geriatr Cogn Disord Extra 2018;8:321 –327 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - October 5, 2018 Category: Geriatrics Source Type: research

The Effects of Dual-Task Training on Patient Outcomes of Institutionalized Elderly Having Chronic Stroke
Conclusion: Based on our findings, walking with dual-task training can be used in addition to conventional stroke rehabilitation aiming to improve balance and mobility.Dement Geriatr Cogn Disord Extra 2018;8:328 –332 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - October 5, 2018 Category: Geriatrics Source Type: research

The Neuropsychiatric Inventory-Diary Rating Scale (NPI-Diary): A Method for Improving Stability in Assessing Neuropsychiatric Symptoms in Dementia
Conclusions: The NPI-Diary showed more appropriate validity and reliability compared to the NPI-NH, when administered in a highly variable sample, as is generally the case in the current health-care setting.Dement Geriatr Cogn Disord Extra 2018;8:306 –320 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - September 10, 2018 Category: Geriatrics Source Type: research

One Size Does Not Fit All: Comparative Diagnostic Accuracy of the Rowland Universal Dementia Assessment Scale and the Mini Mental State Examination in a Memory Clinic Population with Very Low Education
Conclusions: The study provides additional evidence for the usefulness of the RUDAS in a highly illiterate, culturally diverse geriatric outpatient population.Dement Geriatr Cogn Disord Extra 2018;8:290 –305 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - September 2, 2018 Category: Geriatrics Source Type: research

Neurogranin and BACE1 in CSF as Potential Biomarkers Differentiating Depression with Cognitive Deficits from Early Alzheimer ’s Disease: A Pilot Study
Conclusion: The neurogranin/BACE1 ratio in CSF can distinguish between depression and AD among patients with similar cognitive deficits, along with the classic AD biomarkers. Further longitudinal studies are ongoing to identify which biomarkers have prognostic value.Dement Geriatr Cogn Disord Extra 2018;8:277 –289 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - August 6, 2018 Category: Geriatrics Source Type: research

Doctors ’ Knowledge and Attitudes Regarding Enteral Feeding and Eating Problems in Advanced Dementia
Conclusion: We found large gaps in knowledge among doctors about the use of FTs and consequences in patients with advanced dementia.Dement Geriatr Cogn Disord Extra 2018;8:268 –276 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - July 20, 2018 Category: Geriatrics Source Type: research

The Six-Item Cognitive Impairment Test Is Associated with Adverse Outcomes in Acutely Hospitalized Older Patients: A Prospective Cohort Study
Conclusions: In the acute hospital setting, the 6-CIT is associated with 90-day adverse outcome and is an independent predictor of hospital length of stay, new institutionalization, and in-hospital mortality.Dement Geriatr Cogn Disord Extra 2018;8:259 –267 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - July 13, 2018 Category: Geriatrics Source Type: research

Thinking-While-Moving Exercises May Improve Cognition in Elderly with Mild Cognitive Deficits: A Proof-of-Principle Study
Conclusion: Our findings indicate that (1) cognitive-motor exercises induce improved test scores, which is most prominent in elderly with only mild cognitive deficits, and (2) cognitive-motor exercises induce altered visuomotor behavior and slight improvements in measures of general cognition.Dement Geriatr Cogn Disord Extra 2018;8:248 –258 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - July 11, 2018 Category: Geriatrics Source Type: research

Impact of the Sonas Programme on Communication over a Period of 24 Weeks in People with Moderate-to-Severe Dementia
Conclusion: Communication abilities increased with the time of the intervention, but the peak was achieved after 16 weeks, after which the effect levelled out. This suggest that the Sonas programme should be used for a period of at least 16 weeks before evaluating its effect.Dement Geriatr Cogn Disord Extra 2018;8:238 –247 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - June 21, 2018 Category: Geriatrics Source Type: research

Mild Cognitive Impairment Reversion and Progression: Rates and Predictors in Community-Living Older Persons in the Singapore Longitudinal Ageing Studies Cohort
Conclusion: In this relatively younger population, there were higher rates of MCI reversion and lower rates of MCI progression which were predicted by the positive effects of LTA and a higher MMSE score as well as by the deleterious effect of the metabolic syndrome and diabetes.Dement Geriatr Cogn Disord Extra 2018;8:226 –237 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - June 20, 2018 Category: Geriatrics Source Type: research

Clinical Utility of the Cognitive Test for Severe Dementia: Factor Analysis, Minimal Detectable Change, and Longitudinal Changes
Conclusion: Our results indicate that the CTSD could provide a reliable outcome measure in severe dementia.Dement Geriatr Cogn Disord Extra 2018;8:214 –225 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - June 7, 2018 Category: Geriatrics Source Type: research

Severity of Depressive Symptoms and Volume of Superior Temporal Gyrus in People Who Visit a Memory Clinic Unaccompanied
Conclusion: Our results suggest that depressive symptoms of UA subjects demonstrated by the relatively high levels of CES-D scores were primary, because of the inverse association with the normalized volume of bilateral STG. Thus, focusing on the depressive symptoms may be a suitable approach to satisfy potential medical needs of UA subjects with or without memory impairment.Dement Geriatr Cogn Disord Extra 2018;8:207 –213 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - May 31, 2018 Category: Geriatrics Source Type: research

Neuroimaging Characteristics of Small-Vessel Disease in Older Adults with Normal Cognition, Mild Cognitive Impairment, and Alzheimer Disease
Conclusions: These results suggest an association between severity of vascular brain lesions and neurodegeneration.Dement Geriatr Cogn Disord Extra 2018;8:199 –206 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - May 16, 2018 Category: Geriatrics Source Type: research

The Economic Impact of New Therapeutic Interventions on Neuropsychiatric Inventory (NPI) Symptom Scores in Patients with Alzheimer Disease
Conclusion: Treatments that influence specific symptoms within the overall NPI have the potential to improve patient outcomes in a cost-effective way. This model is a useful tool for evaluating target product profiles of drugs with effect on NPI symptoms in early stages of development.Dement Geriatr Cogn Disord Extra 2018;8:158 –173 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - April 26, 2018 Category: Geriatrics Source Type: research

Efficacy and Safety of MLC601 in Patients with Mild to Moderate Alzheimer Disease: An Extension 4-Year Follow-Up Study
Conclusion: The efficacy of treating AD patients with MLC601 over 4 years has been demonstrated in the present study. Overall, it seems that the safety and efficacy of MLC601 is promising compared to currently prescribed treatments.Dement Geriatr Cogn Disord Extra 2018;8:174 –179 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - April 26, 2018 Category: Geriatrics Source Type: research

Imaging Care Requirements: Use of Functional Neuroimaging to Predict Dementia Caregiver Burden
Conclusion: Caregiver burden is strongly related to the extent of frontal or right-predominant parietal or temporal lobe dysfunction. Regional abnormality on perfusion imaging can be used to facilitate identification of individuals who are likely to create a high burden on caregivers.Dement Geriatr Cogn Disord Extra 2018;8:180 –189 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - April 26, 2018 Category: Geriatrics Source Type: research

Driving Cessation in Patients Attending a Young-Onset Dementia Clinic: A Retrospective Cohort Study
Conclusions: YOD diagnosis, female gender, and impairment in praxis have a higher probability for driving cessation in those under 65 years of age with cognitive impairment.Dement Geriatr Cogn Disord Extra 2018;8:190 –198 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - April 26, 2018 Category: Geriatrics Source Type: research

The Link between Potassium and Mild Cognitive Impairment in Mexican-Americans
Conclusion: Our finding suggested a link between serum potassium levels and a diagnosis of MCI in Mexican-Americans. The results of this study support a previous research which has suggested that the risk factors for MCI may vary by ethnicity.Dement Geriatr Cogn Disord Extra 2018;8:151 –157 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - April 25, 2018 Category: Geriatrics Source Type: research