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Effects of Pet Therapy in Elderly Patients with Neurocognitive Disorders: A Brief Review
Conclusion: Although many studies reported positive results, these could not be generalized because of the numerous biases present (e.g., small sample size, lack of methodological rigor, lack of protocol, etc.). Future studies, therefore, should seek to address the limitations found in the analyzed studies.Dement Geriatr Cogn Disord Extra 2021;11:206 –214 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - September 13, 2021 Category: Geriatrics Source Type: research

Determinants of Caregiver Burden in Early-Onset Dementia
Conclusions: Both direct actions (such as increasing social networks and shortening diagnostic delay) and indirect actions aimed at reducing psychological distress (such as increasing the number of caregiver ’s days off work and financial support) should be planned to reduce caregiver’s burden.Dement Geriatr Cogn Disord Extra 2021;11:189 –197 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - August 13, 2021 Category: Geriatrics Source Type: research

Performance of the Rowland Universal Dementia Assessment Scale in Screening Mild Cognitive Impairment at an Outpatient Setting
Conclusion: The RUDAS-Thai performed well in differentiating patients with MCI from normal cognition; however, it was affected by educational level. A score of 25/30 or lower for persons with ≤6 years of education or 26/30 or lower for persons with higher than 6 years of education is the optimal cutoff point for indication of developing MCI.Dement Geriatr Cogn Disord Extra 2021;11:181 –188 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - July 30, 2021 Category: Geriatrics Source Type: research

False Memory and Alzheimer ’s Disease Pathology in Patients with Amnestic Mild Cognitive Impairment: A Study with Amyloid PET
Conclusion: Increased false memory was the only feature to discriminate ADP from non-ADP in individuals with a-MCI. Further studies regarding false memory and its mechanism are warranted.Dement Geriatr Cogn Disord Extra 2021;11:172 –180 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - June 11, 2021 Category: Geriatrics Source Type: research

Commentary for the Elderly in the Pandemic Era
Dement Geriatr Cogn Disord Extra 2021;11:168 –171 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - June 10, 2021 Category: Geriatrics Source Type: research

The Neuroinflammasome in Alzheimer ’s Disease and Cerebral Stroke
Conclusions: AAD can occasionally exacerbate AD and stroke. DDS can alleviate mild cognitive impairment (MCI), early AD and stroke. We clinically confirmed the role of DDS as a neuroinflammasome competitor after stroke. DDS preserved neuronal survival within 24 –55 h in the Seoul Study cohort.Dement Geriatr Cogn Disord Extra 2021;11:159 –167 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - June 10, 2021 Category: Geriatrics Source Type: research

Effects of the Sonas Program on Anxiety and Depression in Nursing Home Residents with Dementia: A 6-Month Randomized Controlled Trial
Conclusion: The Sonas program had no effect on severity of anxiety but a reduction in depressive symptoms was found in PWD.Dement Geriatr Cogn Disord Extra 2021;11:151 –158 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - June 8, 2021 Category: Geriatrics Source Type: research

Parental Age and the Risk for Alzheimer ’s Disease in Offspring: Systematic Review and Meta-Analysis
Conclusions: Overall, this meta-analysis did not demonstrate an association between parental age and the risk of AD in offspring. These findings should be interpreted with caution given the limited power of the overall meta-analysis and the methodological limitations of the underlying studies as in many cases no adjustment for potential confounders was included.Dement Geriatr Cogn Disord Extra 2021;11:140 –150 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - June 8, 2021 Category: Geriatrics Source Type: research

Early Detection and Intervention for Patients with Delirium Admitted to the Department of Internal Medicine: Lessons from a Pilot Initiative
Conclusions: It is often not possible to verify in the emergency room that the cognitive decline is indeed new, that is, is due to delirium, and measures must be taken to verify this point as soon as possible after admission. Due to numerous constraints, the availability of early Mamp;P is often insufficient. Whenever resources are scarce and randomization is avoided, adequate criteria should be found for allocating existing dedicated staff to patients for whom early mobilization is likely to be most beneficial.Dement Geriatr Cogn Disord Extra 2021;11:134 –139 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - June 2, 2021 Category: Geriatrics Source Type: research

Cognitive Profile of Patients with Thalamic Hemorrhage according to Lesion Localization
Conclusion: It was concluded in this study that thalamic hemorrhages affect cognition entirely regardless of the lesion localization. It was also observed that the lateral part of the thalamus was associated with language, the posterior part with memory, and the anteromedial part with the rest of the cognitive subdomains.Dement Geriatr Cogn Disord Extra 2021;11:129 –133 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - May 27, 2021 Category: Geriatrics Source Type: research

Decreased Time on the Nondominant One-Leg Standing Test Associated with Repeated Falls in Older Residents with Healthy Aging, Mild Cognitive Impairment, and Dementia: The Wakuya Project
Conclusion: People with MCI who had fallen repeatedly in the year before the assessment had a significantly lower left OLS time compared to those who had not fallen or had had 1 fall with MCI. None of the other physical measures were associated with past repeat falls including OLS on the dominant right side. No such findings were noted in the CDR 0 and CDR 0+ groups.Dement Geriatr Cogn Disord Extra 2021;11:122 –128 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - May 21, 2021 Category: Geriatrics Source Type: research

Maintenance of the Amygdala-Hippocampal Circuit Function with Safe and Feasible Shaking Exercise Therapy in SAMP-10 Mice
Conclusions: The shaking exercise prevents nonfunctional protein (NFP) accumulation, neuron atrophy, and neuron loss; delays the aging of the amygdala and hippocampus; and maintains the function of the amygdala-hippocampal circuit. It thus enhances emotional processing and cognition functions, the memory of threats, the skillful confrontation of threats, and proper self-protection from danger.Dement Geriatr Cogn Disord Extra 2021;11:114 –121 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - May 19, 2021 Category: Geriatrics Source Type: research

Assessing the Possible Influence of Residues of Ractopamine, a Livestock Feed Additive, in Meat on Alzheimer Disease
The feed additive ractopamine, a β-adrenergic agonist, has been approved for use in livestock for nearly 2 decades. Studies of its possible adverse effects in humans have concentrated exclusively on cardiovascular disease and cardiovascular functional disorders in the past. In this article, whether and how ractopamine may affect n eurodegeneration, either to promote or to reduce the incidence of Alz­heimer disease, will be discussed based on the recent controversial findings that β-adrenoreceptor activation not only can stimulate Alzheimer-pathogenic amyloid-β accumulation but also are able to enhance hippocampal neuro...
Source: Dementia and Geriatric Cognitive Disorders Extra - May 7, 2021 Category: Geriatrics Source Type: research

Factors Associated with Home Care Outcomes among Community-Dwelling Older Adult Patients with Dementia
Conclusions: Further research is required to investigate the impacts of multiple social and environmental factors on home care outcomes among PWD; which can eventually be used by nurses and family caregivers when providing care for older adult PWD.Dement Geriatr Cogn Disord Extra 2021;11:99 –109 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - May 6, 2021 Category: Geriatrics Source Type: research

Characteristics of Regional Cerebral Blood Flow in Alzheimer Disease and Amnestic Mild Cognitive Impairment by Single-Photon Emission Computerized Tomography: A Cross-Sectional Study
Conclusion: Based on the analysis of the values obtained, it was inferred that the rCBF undergoes reduction and elevation in aMCI and AD patients.Dement Geriatr Cogn Disord Extra 2021;11:91 –98 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - May 6, 2021 Category: Geriatrics Source Type: research