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Physical Fitness in Older People Recently Diagnosed with Cognitive Impairment Compared to Older People Recently Discharged from Hospital
Background/Aims: There is evidence of an association between cognitive function and physical fitness. The aim of this study was to compare physical fitness in patients with cognitive impairment with a group of older people recently discharged from hospital.Methods: A cross-sectional study with 98 patients recently diagnosed with cognitive impairment and 115 patients recently discharged from hospital. Associations between the study group variable and different components in the Senior fitness test were examined, controlling for demographic factors and comorbidity.Results: The group recently diagnosed with cognitive impairme...
Source: Dementia and Geriatric Cognitive Disorders Extra - September 9, 2016 Category: Geriatrics Source Type: research

Does Schizophrenia in Offspring Increase the Risk of Developing Alzheimer's Dementia
Conclusion: The finding of no familial coaggregation between schizophrenia and Alzheimer's dementia may suggest that no common etiology between the disorders exists. This may indicate that the excess risk of dementia in individuals with schizophrenia is a by-product of the higher rates of somatic comorbidity and adverse health risk factors among these individuals.Dement Geriatr Cogn Disord Extra 2016;6:361-373 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - August 22, 2016 Category: Geriatrics Source Type: research

Qualitative Assessment of Instrumental Activities of Daily Living in Older Persons with Very Mild Dementia: The Kurihara Project
Conclusion: We suggest using both quantitative/qualitative IADL scales for assessing older adults with very mild dementia.Dement Geriatr Cogn Disord Extra 2016;6:374-381 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - August 19, 2016 Category: Geriatrics Source Type: research

Does Schizophrenia in Offspring Increase the Risk of Developing Alzheimer's Dementia?
Conclusion: The finding of no familial coaggregation between schizophrenia and Alzheimer's dementia may suggest that no common etiology between the disorders exists. This may indicate that the excess risk of dementia in individuals with schizophrenia is a by-product of the higher rates of somatic comorbidity and adverse health risk factors among these individuals.Dement Geriatr Cogn Disord Extra 2016;6:361-373 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - August 19, 2016 Category: Geriatrics Source Type: research

Decreased Physical Activity Associated with Executive Dysfunction Correlates with Cognitive Impairment among Older Adults in the Community: A Retrospective Analysis from the Kurihara Project
Conclusion: PA was related to the burden of executive function in patients with mild cognitive impairment; however, in patients with dementia, PA was related to both the burden of executive function and motor intensity.Dement Geriatr Cogn Disord Extra 2016;6:350-360 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - August 16, 2016 Category: Geriatrics Source Type: research

Modifiable Factors Associated with Cognitive Impairment in 1,143 Japanese Outpatients: The Project in Sado for Total Health (PROST)
This study aimed to determine modifiable factors for cognitive impairment in a Japanese hospital-based population.Methods: Subjects of this cross-sectional study were 1,143 patients of Sado General Hospital (Niigata, Japan) registered in the Project in Sado for Total Health (PROST) between June 2008 and September 2014. We assessed disease history, body mass index (BMI), leisure time physical activity, walking time, smoking and drinking habits, and consumption of vegetables, fruits, and green tea as predictors, with cognitive impairment defined by the Mini-Mental State Examination (score (Source: Dementia and Geriatric Cogn...
Source: Dementia and Geriatric Cognitive Disorders Extra - August 11, 2016 Category: Geriatrics Source Type: research

Progranulin Levels in Plasma and Cerebrospinal Fluid in Granulin Mutation Carriers
Conclusions: Plasma PGRN is relatively stable over 1 week and therefore seems suitable for treatment monitoring of PGRN-enhancing agents. Since plasma PGRN only moderately correlated with CSF PGRN, CSF sampling will additionally be needed in therapeutic trials.Dement Geriatr Cogn Disord Extra 2016;6:330-340 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - July 21, 2016 Category: Geriatrics Source Type: research

Using the Disease State Fingerprint Tool for Differential Diagnosis of Frontotemporal Dementia and Alzheimer's Disease
Conclusions: DSI is a promising computer-assisted biomarker approach for aiding in the diagnostic process of dementing diseases. Here, DSI separates controls from dementia and differentiates between AD and FTD.Dement Geriatr Cogn Disord Extra 2016;6:313-329 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - July 21, 2016 Category: Geriatrics Source Type: research

Low Cerebrospinal Fluid Amyloid-Beta Concentration Is Associated with Poorer Delayed Memory Recall in Women
Conclusions: CSF biomarkers correlate with delayed memory scores in CERAD-NB in women, and women may have more actual AD pathology at the time of the investigations than men.Dement Geriatr Cogn Disord Extra 2016;6:303-312 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - July 19, 2016 Category: Geriatrics Source Type: research

Low Leptin Availability as a Risk Factor for Dementia in Chilean Older People
Conclusion: Lower availability of free leptin was found in demented than in nondemented people, suggesting a role of leptin in cognition.Dement Geriatr Cogn Disord Extra 2016;6:295-302 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - July 15, 2016 Category: Geriatrics Source Type: research

Increased Cerebrospinal Fluid Levels of Ubiquitin Carboxyl-Terminal Hydrolase L1 in Patients with Alzheimer's Disease
Conclusion: Our main findings support that the UPS pathway may be impaired in AD, and UCH-L1 may serve as an additional CSF biomarker for AD.Dement Geriatr Cogn Disord Extra 2016;6:283-294 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - July 14, 2016 Category: Geriatrics Source Type: research

The Diagnostic Utility of the NINDS-CSN Neuropsychological Battery in Memory Clinics
Conclusion: The NINDS-CSN neuropsychological battery can be applied in memory clinics and effectively discriminate between cognitively intact individuals and those with cognitive impairments of varying severity. Furthermore, level of education should be taken into consideration when choosing protocols with different lengths for cognitive assessment.Dement Geriatr Cogn Disord Extra 2016;6:276-282 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - July 14, 2016 Category: Geriatrics Source Type: research

Does MRI Increase the Diagnostic Confidence of Physicians in an Outpatient Memory Clinic
Conclusion: MRI is a useful diagnostic tool in everyday practice of diagnosing cognitive disorders.Dement Geriatr Cogn Disord Extra 2016;6:242-251 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - June 27, 2016 Category: Geriatrics Source Type: research

Does MRI Increase the Diagnostic Confidence of Physicians in an Outpatient Memory Clinic?
Conclusion: MRI is a useful diagnostic tool in everyday practice of diagnosing cognitive disorders.Dement Geriatr Cogn Disord Extra 2016;6:242-251 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - June 24, 2016 Category: Geriatrics Source Type: research

Creative Music Therapy in an Acute Care Setting for Older Patients with Delirium and Dementia
Conclusion: These results suggest that CMT holds much promise to improve mood and engagement of PtDD in an acute hospital setting. CMT can also be scheduled into the patients' daily routines or incorporated into other areas of care to increase patient compliance and cooperation.Dement Geriatr Cogn Disord Extra 2016;6:268-275 (Source: Dementia and Geriatric Cognitive Disorders Extra)
Source: Dementia and Geriatric Cognitive Disorders Extra - June 24, 2016 Category: Geriatrics Source Type: research