The role of JNK phosphorylation as a molecular target to enhance adenovirus replication, oncolysis and cancer therapeutic efficacy.

This study has demonstrated for the first time that JNK is an intriguing molecular marker associated with enhanced Ad virotherapy efficacy, influencing future Ad vector design.
PMID: 30067431 [PubMed - as supplied by publisher]

Source: Cancer Biology and Therapy - August 1, 2018 Category: Cancer & Oncology Authors: Wechman SL, Rao XM, Gomez-Gutierrez JG, Zhou HS, McMasters KM Tags: Cancer Biol Ther Source Type: research