Variability in lung cancer response to ALK inhibitors cannot be explained by the diversity of ALK fusion variants.

In conclusion, this study revealed that distinct ALK translocation variants render similar clinical responsiveness to ALK inhibitors.
PMID: 30071258 [PubMed - as supplied by publisher]

Source: Biochimie - July 30, 2018 Category: Biochemistry Authors: Mitiushkina NV, Tiurin VI, Iyevleva AG, Kholmatov MM, Filippova EA, Moiseyenko FV, Levchenko NE, Sardaryan IS, Odintsova SV, Lozhkina AM, Volkov NM, Karaseva NA, Moiseyenko VM, Orlov SV, Imyanitov EN Tags: Biochimie Source Type: research