Opioids and Cardiac Arrhythmia: A Literature Review

Conclusion: The cardiac arrhythmogenicity of various opioids is different. Methadone has a higher capability to induce long QT interval and dangerous arrhythmias in conventional doses than others. To reduce of arrhythmogenic risk, high doses of opioids must be used cautiously with periodic monitoring of electrocardiogram in high-risk consumers such as patients under opioid maintenance treatment.
Source: Medical Principles and Practice - Category: Internal Medicine Source Type: research