Discriminative power of intra-retinal layers in early multiple sclerosis using 3D OCT imaging

ConclusionOur 3D-OCT data demonstrated that TRV, mRNFL and GCIPL allow discrimination between ON and NON patients in a cross-sectional analysis. However, the subsequent retinal atrophy pattern diverges in the initial phase of MS: Prior ON promotes sustained axonal thinning over time indicated by mRNFL loss, whereas longitudinal measurement of GCIPL volume better depicts continuous retrograde neurodegeneration in NON patients in early-stage MS.

http://link.springer.com/10.1007/s00415-018-8988-3

Source: Journal of Neurology - August 2, 2018 Category: Neurology Source Type: research