Incidence and dosimetric parameters of pediatric brainstem toxicity following proton therapy.

Conclusion. Utilization of current national brainstem dose guidelines is associated with a low risk of brainstem toxicity in pediatric patients. For young patients with posterior fossa tumors, particularly those who undergo aggressive surgery, our data suggest more conservative dosimetric guidelines should be considered. PMID: 25279957 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/25279957?dopt=Abstract

Source: Acta Oncologica - October 3, 2014 Category: Cancer & Oncology Authors: Indelicato DJ, Flampouri S, Rotondo RL, Bradley JA, Morris CG, Aldana PR, Sandler E, Mendenhall NP Tags: Acta Oncol Source Type: research