Associations of ESR1 and ESR2 gene polymorphisms with metabolic syndrome and its components in postmenopausal women

Metabolic syndrome (MS) is a constellation of risk factors, which, when not treated, leads to the development of type 2 diabetes mellitus (T2DM) and coronary heart disease (CHD). It is a prevalent condition, which is associated with the growing epidemic of sedentary lifestyle[1]. MS is diagnosed when at least three out of five following risk factors are present: central obesity, elevated serum triglycerides, low HDL cholesterol concentrations, impaired fasting glucose and elevated systolic (SBP) or/and diastolic blood pressure (DBP)[2].

Source: Maturitas - July 3, 2018 Category: Primary Care Authors: Karolina Ku źbicka, Dominik Rachoń, Anna Woziwodzka, Magda Rybicka, Krzysztof Piotr Bielawski Source Type: research