Diabetic Vascular Calcification Mediated by the Collagen Receptor Discoidin Domain Receptor 1 via the Phosphoinositide 3-Kinase/Akt/Runt-Related Transcription Factor 2 Signaling Axis.

CONCLUSIONS: These novel findings demonstrate that DDR1 promotes RUNX2 activity and atherosclerotic vascular calcification in diabetes mellitus via phosphoinositide 3-kinase/Akt signaling. PMID: 29930002 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29930002?dopt=Abstract

Source: Arteriosclerosis, Thrombosis and Vascular Biology - June 21, 2018 Category: Cardiology Authors: Lino M, Wan MH, Rocca AS, Ngai D, Shobeiri N, Hou G, Ge C, Franceschi RT, Bendeck MP Tags: Arterioscler Thromb Vasc Biol Source Type: research