DNA damage predicts prognosis and treatment response in colorectal liver metastases superior to immunogenic cell death and T cells

Conclusion: In contrast to preclinical models, DNA damage inversely correlated with ICD and its associated T cell infiltrate and potentially serves as a therapeutic target in CLM.

Source: Theranostics - June 20, 2018 Category: Molecular Biology Authors: Johannes Laengle, Judith Stift, Agnes Bilecz, Brigitte Wolf, Andrea Beer, Balazs Hegedus, Stefan Stremitzer, Patrick Starlinger, Dietmar Tamandl, Dietmar Pils, Michael Bergmann Tags: Research Paper Source Type: research