Fighting breast cancer stem cells through the immune-targeting of the xCT cystine –glutamate antiporter

In conclusion, our approach based on the comparison of the transcriptome of tumorspheres and parental cells allowed us to identify a novel CSC-related target and to develop preclinical therapeutic approaches able to impac t on CSC biology, and therefore, hampering tumor growth and dissemination.
Source: Cancer Immunology, Immunotherapy - Category: Cancer & Oncology Source Type: research