Brain neurotransmitter transporter/receptor genomics and efavirenz central nervous system adverse events

Conclusion Efavirenz-related CNS adverse events were not associated with predicted neurotransmitter transporter/receptor gene expression levels in brain or with polymorphisms in these genes. Variable susceptibility to efavirenz-related CNS adverse events may not be explained by brain neurotransmitter transporter/receptor genomics.
Source: Pharmacogenetics and Genomics - Category: Genetics & Stem Cells Tags: Original Article Source Type: research