Molecular Characterization of Methicillin-Resistant Staphylococcus aureus Isolates, Isolated from a Burn Hospital in Southwest Iran in 2006 and 2014.

Conclusion: The predominance of ST-239 in this region during the last eight years is a major concern. It also has a disturbing impact on the management of staphylococcal infections. Moreover, the SCCmec type IV strain is able to disseminate rapidly in hospital environments, demanding an improvement in infection-control policy. PMID: 29887890 [PubMed]
Source: International Journal of Microbiology - Category: Microbiology Tags: Int J Microbiol Source Type: research

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Conclusions: A high rate of PVL toxin gene was detected amongS. aureus strains and a high prevalence of antimicrobial resistant strains was observed.
Source: The Journal of Infection in Developing Countries - Category: Infectious Diseases Source Type: research
ConclusionsPatient privacy curtains became progressively contaminated with bacteria, including MRSA. Between days 10 and 14 after being hung, curtains showed increased MRSA positivity. This may represent an opportune time to intervene, either by cleaning or replacing the curtains.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
Our study aims to lay groundwork for future use of skin microbiota transplantation (SMT) as treatment for skin diseases with a known component of microbial dysbiosis (e.g., atopic dermatitis, recurrent methicillin-resistant Staphylococcus aureus [MRSA] folliculitis, and burn wound colonization and infection). Our group ’s whole-microbiota transplantation joins the conversation begun by investigators focusing on enriched skin microbiota transplant. With 4 healthy volunteers (mean [SD] age 29.3 [4.6] years; 2 [50%] female), we adapted a simple technique for harvesting and delivering a transplant, moving microbiota from...
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Burn infections pose a serious obstacle to recovery. To investigate and analyze the antimicrobial resistance and distribution of pathogenic bacteria among hospitalized burn patients. A 3-year retrospective study was conducted in the southeast of China. The electronic medical records system was used to collect all clinical data on 1449 hospitalized patients from Fujian Medical University Union Hospital, the 180th Hospital of Chinese People's Liberation Army (PLA), the 92nd Hospital of PLA, and the First Hospital of Longyan City. A total of 1891 strains of pathogenic bacteria were detected from 3835 clinical specimens, and...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
jun Yang Wenyu Han Jingmin Gu Staphylococcus aureus (S. aureus) is a common and dangerous pathogen that causes various infectious diseases. Skin damage, such as burn wounds, are at high risk of Staphylococcus aureus colonization and infection, which increases morbidity and mortality. The phage lysin LysGH15 exhibits highly efficient lytic activity against methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus (MSSA) strains. Apigenin (api) significantly decreases haemolysis of rabbit erythrocytes caused by S. aureus and shows anti-inflammatory function. LysGH15 and api were added to Aquaphor t...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Conclusions Patient privacy curtains became progressively contaminated with bacteria, including MRSA. Between days 10 and 14 after being hung, curtains showed increased MRSA positivity. This may represent an opportune time to intervene, either by cleaning or replacing the curtains.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
Conclusions The results of this study indicate that the prevalence of MRSA among burn patients is very high in Iran. Thus, a comprehensive infection control strategy based on hand hygiene, education and training in antibiotic prescribing, environmental cleaning, contact precautions, good antibiotic stewardship and an active surveillance system on the basis of international criteria is urgently needed.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
In this study, the anti-infection activity of AgNP immobilized biomaterials was evaluated, facilitated by argon plasma grafting technology and activated by bacterial colonization. The modified materials generated in this study showed excellent specificity and were active against both Gram-positive and Gram-negative biofilm forming bacteria, including methicillin-resistant Staphylococcus aureus, Staphylococcus epidermidis, and Escherichia coli. The anti-infection biomaterials developed in this study demonstrate several attractive advantages in comparison to traditional anti-bacterial surfaces loaded with antibiotics or othe...
Source: Biofouling - Category: Molecular Biology Authors: Tags: Biofouling Source Type: research
Conclusion A comprehensive concept is required to control the spread of all multidrug-resistant micro-organisms including MRSA on a burn unit. Where patients colonized or infected with MRSA appear to be the main reservoir, transfer of these patients to other units, or temporary closure of the unit, accompanied by intensive cleaning are very effective measures to stop transmission events.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
In conclusion, our study suggests that MRSA infection is serious in our burn center, but presented decreased trend over time. Most of MRSA isolates in our center presented the same virulence factor profile. More attention should be attached to nosocomial infection in burn medical center. Antimicrobials susceptibility changing over time was observed. Antimicrobials susceptibility monitoring is necessary and helps to select appropriate drugs against MRSA infections.
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
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