Intravenous morphine versus intravenous paracetamol after cardiac surgery in neonates and infants: a study protocol for a randomized controlled trial

This study will focus on the reduction, or replacement, of morphine by IV paracetamol in children (0 –36 months old) after cardiac surgery. The results of this study will form the basis of a new pain management algorithm and will be implemented at the participating ICUs, resulting in an evidence-based guideline on post-operative pain after cardiac surgery in infants who are 0–36 months old.Trial registrationDutch Trial Registry (www.trialregister.nl):NTR5448 on September 1, 2015. Institutional review board approval (MEC2015 –646), current protocol version: July 3, 2017
Source: Trials - Category: Research Source Type: clinical trials